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Effect of statins on fasting glucose in non-diabetic individuals: nationwide population-based health examination in KoreaCardiovascular Diabetology volume 17, Article number: 155 (2018)
Conclusions
More adherent and intensive use of statins was significantly associated with an increase in fasting glucose of non-diabetic individuals. In subgroup analysis of individual statins, use of atorvastatin, rosuvastatin, pitavastatin and simvastatin had significant association with increase in fasting glucose. Pravastatin, lovastatin, and fluvastatin had non-significant trend toward an increased fasting glucose.
Our findings suggest the medication class effect of statins inducing hyperglycemia.https://cardiab.biomedcentral.com/artic ... 018-0799-4Edit, ihan jännää luettavaa:
In our study, all classes of statins were associated with an increase in fasting glucose although the effects of pravastatin, lovastatin, and fluvastatin were not significant. In our data, the hyperglycemic effects of pitavastatin does not seem to be lower than that of other statins in contrast to the favorable reports for pitavastatin on glucose metabolism. A recent retrospective cohort study in Korea also reported that pitavastatin had the highest risk of new-onset DM compared to other statins [69].