Kumpi on suurempi syyllinen insuliiniresistenssin ja tyypin 2 diabeteksen yleistymisessä: hiilarit vai PUFA? Paul Saladino ja Ben Bikman diskuteeraavat.
Benjamin Bikman earned his PhD in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore studying metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the origins and consequences of metabolic disorders, including obesity and diabetes, with a particular emphasis on the role of insulin. He frequently publishes his research in peer-reviewed journals and presents at international science and public meetings.
Time Stamps
0:11:14 Podcast Begins
0:11:54 Ben's Background
0:17:53 The root of chronic disease
0:25:38 All about insulin
0:31:14 Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification
https://www.semanticscholar.org/paper...
0:31:51 Insulin stops lipolisis
0:34:35 Insulin's affect on the liver
0:40:10 Insulin and muscle cells
0:43:20 Why you want to increase protein as you age
0:48:47 Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population
https://www.ncbi.nlm.nih.gov/pmc/arti....
0:51:00 Animal-based diets optimize muscle protein sythesis
0:55:12 Industrial Seed oils have a fantastic publicist
0:58:05 Do carbs drive metabolic dysfunction?
1:07:07 Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man
https://link.springer.com/article/10....
1:07:42 How linoleic acid drives metabolic dysfunction
1:09:32 How linoleic acid drives metabolic dysfunction.
1:11:47 Low serum insulin in traditional Pacific Islanders--the Kitava Study
https://www.metabolismjournal.com/art...
1:14:29 Carbs are not to blame
1:19:05 Thriving is dependent on micronutrients
1:22:19 The secret to overcoming plateaus on low carb diets
1:25:28 Epidemiological studies in a total highland population, Tukisenta, New Guinea: Cardiovascular disease and relevant clinical, electrocardiographic, radiological and biochemical findings
https://www.sciencedirect.com/science...
1:25:58 Classification of Obesity with Respect to Morbidity
https://journals.sagepub.com/doi/abs/...
1:27:46 Does fructose make us fat?
1:28:32 What makes honey different?
1:30:45 Effect of honey in preventing gingivitis and dental caries in patients undergoing orthodontic treatment
https://www.ncbi.nlm.nih.gov/pmc/arti....
1:31:11 Substituting Honey for Refined Carbohydrates Protects Rats from Hypertriglyceridemic and Prooxidative Effects of Fructose
https://academic.oup.com/jn/article/1...
1:32:15 Effect of fructose on body weight in controlled feeding trials
https://www.ncbi.nlm.nih.gov/books/NB...
1:33:21 Oral health in transition: the Hadza foragers of Tanzania
https://journals.plos.org/plosone/art...
1:34:53 Hyperplastic vs hypertrophic fat cell growth
1:40:01 FADH2, NADH, and mitochondrial magic
1:43:27 Diet fat composition alters membrane phospholipid composition, insulin binding, and glucose metabolism in adipocytes from control and diabetic animals
https://www.jbc.org/content/265/19/111431:43:27 Unwanted insulin sensitivity
1:50:01 Dietary Stearic Acid Leads to a Reduction of Visceral Adipose Tissue in Athymic Nude Mice
https://www.researchgate.net/publicat...
1:52:16 dietary stearic acid regulates mitochondria in vivo in humans
https://www.nature.com/articles/s4146...