Tutkimuskatsaus Cambridgesta vertaili niitä kahta strategiaa, joilla tyypin 2 diabetes on tutkitusti saatu remisioon eli aidatun kehäneliön yhteen nurkkaukseen asettuu järkyttävä laihdutuskuuri ateriankorvikkeilla ("Taylorin kitukuuri") ja toiseen vhh/keto, jossa vähähiilarisia herkkuja syödään ad libitum.
Voittajaa ei varsinaisesti julisteta: " Trials that restricted energy intake were not superior to those that allowed ad libitum low-carbohydrate feeding at 12 and 24 months."
Vaan kumpi strategia mahtaisi olla pitemmän päälle mukavammin noudatettavissa? Luulen, ettei kukaan voi loppuelämänsä ajan kituilla. Äkkilaihdutuskuurilla saavutetun remission pysyvyydestä sen jälkeen kun kuurilta on siirrytty normisyömiseen ei ole toistaiseksi pitempiaikaista näyttöä. Keto/vhh:lla saavutetun remission pysyvyydestä ruokavaliota jatkuvasti noudatettaessa on runsaasti anekdoottista näyttöä ja pian tulee Virralta tutkittua näyttöä pysyvyydestä viiden vuoden ajalta.
Iso plussa tälle tutkimukselle siitä, että ihan suoraan myönnetään MOLEMPIEN strategioiden olevan VÄHÄHIILIHYDRAATTISIA.
Linkki Cambridgen tutkimukseen:
Restricting carbohydrates and calories in the treatment of type 2 diabetes: a systematic review of the effectiveness of ‘low-carbohydrate’ interventions with differing energy levelsLainaa:
Abstract
There are two proven dietary approaches to shift type 2 diabetes (T2D) into remission: low-energy diets (LEDs) and low-carbohydrate diets (LCDs). These approaches differ in their rationale and application yet both involve carbohydrate restriction, either as an explicit goal or as a consequence of reducing overall energy intake. The aims of this systematic review were to identify, characterise and compare existing clinical trials that utilised ‘low-carbohydrate’ interventions with differing energy intakes. Electronic databases CENTRAL, CINAHL, Embase, MEDLINE and Scopus were searched to identify controlled clinical trials in adults with T2D involving low-carbohydrate intake (defined as <130 g carbohydrate/d) and reporting weight and glycaemic outcomes. The initial database search yielded 809 results, of which fifteen studies met the inclusion criteria. Nine out of fifteen studies utilised LCDs with moderate or unrestricted energy intake. Six trials utilised LEDs (<1200 kcal/d), with all except one incorporating meal replacements as part of a commercial weight loss programme. Interventions using both restricted and unrestricted (ad libitum) energy intakes produced clinically significant weight loss and reduction in glycated haemoglobin (HbA1c) at study endpoints. Trials that restricted energy intake were not superior to those that allowed ad libitum low-carbohydrate feeding at 12 and 24 months. An association was observed across studies between average weight loss and reduction in HbA1c at 6, 12 and 24 months, indicating that sustained weight loss is key to T2D remission. Further research is needed to specifically ascertain the weight-independent effects of carbohydrate restriction on glycaemic control in T2D.
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