Tutkimuskatsaus ja metatutkimus: "Erittäin niukkaenergiainen ketoruokavalio VLCKD pudottaa painoa tehokkaasti ja turvallisesti".Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis.
Twelve studies were included. VLCKD was associated with weight losses of -10.0 kg (I2 = 6%) and - 15.6 kg (I2 = 37%) in studies with a ketogenic phase up to and of at least four weeks, respectively. The weight lost during the ketogenic phase was stable in the subsequent follow-up up to two years (p = 0.12). Also, VLCKD was associated with reductions of BMI (-5.3 kg/m2), waist circumference (-12.6 cm), HbA1c (-0.7%), total cholesterol (-28 mg/dl), triglycerides (-30 mg/dl), AST (-7 U/l), ALT (-8 U/l), GGT (-8 U/l), systolic and diastolic blood pressure (-8 and - 7 mmHg, respectively). No changes in LDL cholesterol, HDL cholesterol, serum creatinine, serum uric acid and serum potassium were found. Serum sodium increased during VLCKD (+1.6 mEq/l). The overall prevalence of patients discontinuing VLCKD was 7.5% and this was similar to patients undergoing a low calorie diet (p = 0.83). The present review supports the use of VLCKD as an effective strategy for the management of overweight and obesity. Future guidelines should include a specific recommendation for this intervention.
Ketoilu laihduttaa toki ilman kituiluakin, eli energian saannin puristamista alle 800 Kcal/d:n. Kuten Diet Doctor muistuttaa, ketoilu vähentää ruokahalua ja tapaa johtaa spontaaniin energiansaannin vähentämiseen.Diet Doctor: New review: very-low-calorie ketogenic diets are effective for weight loss